Nausea can be a disruptive and exhausting symptom. Whether it’s the result of a medical treatment like chemotherapy, chronic illness, anxiety, or even motion sickness, finding lasting relief can be difficult. For many people, cannabis offers a gentler alternative to traditional pharmaceuticals-especially when nausea becomes part of daily life.
At Citi Roots, located just minutes from Princeton and Plainsboro, NJ, we often help customers navigate the wide world of cannabis with questions like, “Which strain can help with an unsettled stomach?” This guide takes a closer look at the best cannabis strains for nausea relief and how to choose one that suits your individual needs.
How Cannabis May Help with Nausea
The human body has a complex system called the endocannabinoid system (ECS) that helps regulate various functions-mood, appetite, pain, and even nausea. Compounds in cannabis, specifically THC (tetrahydrocannabinol) and CBD (cannabidiol), interact with this system to provide soothing effects.
For nausea, THC is especially significant. Research has shown that THC can reduce nausea and vomiting, especially in patients undergoing cancer treatments. It’s so effective that synthetic versions of THC (like dronabinol) have been prescribed for years in medical settings. CBD, while less psychoactive, may also help ease nausea by reducing inflammation and anxiety.
Unlike conventional medications, many users appreciate that cannabis offers this relief without harsh side effects or dependence risks-when used responsibly.
Cannabinoids and Terpenes: Natural Helpers Against Nausea
Not all cannabis products work the same. Two major factors play a role:
- Cannabinoids:
- THC: Often the go-to for nausea and appetite loss. It’s quick-acting and relaxing.
- CBD: May ease anxiety-driven nausea without the “high.”
- THC: Often the go-to for nausea and appetite loss. It’s quick-acting and relaxing.
- Terpenes: These are aromatic compounds that also offer therapeutic effects. For nausea relief, watch for:
- Limonene – Found in citrusy strains, can uplift mood and calm the stomach.
- Myrcene – Has soothing, sedative qualities; common in indica-dominant strains.
- Limonene – Found in citrusy strains, can uplift mood and calm the stomach.
Understanding these components helps you make better-informed choices when picking a strain.

Top Cannabis Strains for Nausea Relief
The following strains are among the most commonly used and well-reviewed by both medical and recreational users for nausea relief. Some are THC-heavy; others balance both THC and CBD.
1. Granddaddy Purple (Indica)
This classic indica is popular for evening use due to its relaxing and sedative effects. Many users say it settles the stomach while easing muscle tension and discomfort.
2. Sour Diesel (Sativa)
Fast-acting and energizing, Sour Diesel is ideal for daytime relief. Its uplifting effects may be beneficial if your nausea is linked to stress or low energy.
3. Jack Herer (Sativa-dominant Hybrid)
Known for its mental clarity and mild body relief, Jack Herer offers nausea support without heavy sedation, making it a great choice for those needing to stay productive.
4. ACDC (CBD-dominant Hybrid)
With very low THC and high CBD content, ACDC is well-suited for users who want relief without feeling high. This strain may be particularly helpful for anxiety-related nausea.
5. Harlequin (CBD:THC Balanced)
This balanced hybrid has a roughly 1:1 CBD to THC ratio, making it gentle yet effective. Many users report a mellow calming sensation that eases both stomach discomfort and mental tension.
6. Gelato (Hybrid)
Flavorful and aromatic, Gelato delivers a body-calming effect that can reduce nausea while offering a sweet taste that’s easy on a sensitive palate.
7. Northern Lights (Indica)
A go-to for patients dealing with sleep disruption due to nausea or pain. Northern Lights brings a calming body high and restful sedation.
Note: Availability may vary, but many of these strains can be found at Citi Roots. Speak with one of our budtenders to see which are currently in stock or explore our online menu.

Choosing the Right Strain for You
Every person’s body chemistry is different, and so are the reasons behind nausea. When selecting a cannabis product for relief, consider:
- The cause of nausea: Is it from anxiety, a medical condition, or a temporary upset?
- Time of day: Sativa strains may be better for daytime use, while indicas work well at night.
- THC tolerance: If you’re new to cannabis or prefer a mild experience, start with lower-THC or balanced strains.
The team at Citi Roots is always ready to help you find a strain that meets your needs without overwhelming you.
Fast-Acting Ways to Use Cannabis for Nausea
How you consume cannabis can impact how quickly and effectively it works.
Popular consumption methods:
- Vaporizing: Offers near-instant relief. Great for sudden onset nausea.
- Tinctures: Fast-absorbing drops placed under the tongue. Easy to dose and discreet.
- Pre-rolls: Convenient and fast-acting, but may not be ideal if smoking irritates your stomach or throat.
- Edibles: Longer-lasting but slower to kick in (30–90 minutes). Better for chronic or ongoing nausea.
Your choice will depend on how quickly you need relief and your comfort with different formats.
A Few Considerations Before You Begin
While cannabis is a natural option, a few precautions are important:
- Start low, go slow: Especially if you’re new or trying a high-THC strain.
- Consult your doctor: If nausea is persistent or related to a chronic condition, get a professional opinion.
- Watch for dehydration: Some strains can cause dry mouth, so drink plenty of fluids.
It’s also a good idea to journal your experiences. Tracking how different strains affect your nausea can help you identify what works best.

Why Locals Trust Citi Roots for Relief
As a disabled veteran-owned dispensary near Princeton and Plainsboro, NJ, Citi Roots prides itself on offering:
- A curated selection of high-quality cannabis products-from flower to tinctures
- A team of friendly, knowledgeable budtenders ready to guide your experience
- Easy online ordering and a welcoming in-store environment
- A personalized experience-we listen, ask questions, and help you feel confident in your choice
Many of our customers come in seeking relief for medical symptoms like nausea, and leave feeling more informed and supported.
Final Thoughts
Finding the best cannabis strain for nausea doesn’t have to be complicated. With the right knowledge and support, many people discover that cannabis can provide much-needed comfort and control in their daily lives.
If you’re considering cannabis as a natural way to ease your nausea, we invite you to visit Citi Roots. Our team is happy to walk you through the options, whether you’re experienced or just getting started.
Browse our online menu or stop by our dispensary near Princeton and Plainsboro to learn more.